In vivo pharmacokinetics tests and sample harvest
Model | Assay Name | Measurements |
1. Wild type mice | 1. P.O (e.g., gavage) | 1. Drugs or biomarker levels in plasma and key organ tissues (via subcontractors) |
2. Transgenic mice | 2. S.C. | 2. Histopathology and immunohistochemistry (IHC, via subcontractor) |
3. Cannulated rodents | 3. I.P. | |
4. Control | 4. I.V. | |
5. Treatment | 5. I.T. (intrathecal injection) | |
6. Mini-pump |