Collaborations
1. Stanford University School of Medicine
- Development of automated neurobehavioral assay for rodent stroke model assessments (with Prof. R. Giffard, two publications, Stroke 2011, 2013)
- Treatment of neuropathic pain with dissolvable microneedles containing peptide GPCR antagonists (with Prof. D. Yeomans)
- Molecular changes in the aging systemic milieu using parabiosis mice (studies led by Prof. A. Wyss-Coray, two publications, Nature, 2011; Nat. Med., 2014)
- Gut-derived factors promote neurogenesis of CNS-neural stem cells and nudge their differentiation to an enteric-like neuronal phenotype (studies let by J Pasricha P, Gastrointestinal and Liver Physiology, 2011, Molecular Pain, 2012)
- Reduced locomotor activity correlates with increased severity of arthritis in a mouse model of antibody-induced arthritis (with Prof. E. Mellins, Open J Rheumatol Autoimmune Dis., 2014)
2. Harvard Medical School
- Developing a visual assessment system for retinal function/drug discovery (with Prof. D. Chen and Prof. G. Luo, Schepens Eye Research Institute Massachusetts Eye and Ear)
- Study the interaction between nociceptin/orphanin FQ and hypocretin/orexin systems in modulation of stress-induced analgesia in rats, and tracer-suicide enzyme-prodrug for selective lesions of particular neural pathways. (with Prof. D. Gerashchenko, Neuropharmacology 2011, Harvard Medical School/VA Medical Center)
3. University of California Los Angeles, David Geffen School of Medicine
- Nicotine delivery to rodents with lung alveolar region-targeted aerosol technology (With Dr. M. Shao, Nicotine Tob Res, 2013)
4. University of California, Davis
- Development of novel tricyclic pyrone drugs for treatment of Alzheimer’s disease (With Prof. L. Jin)
5. Kansas State University
- Development of novel tricyclic pyrone drugs for treatment of Alzheimer’s disease and
- Development of novel Tetracyclic Terpenes for for treatment of hypertension (With . Prof. H. Hua, Bioorganic & Medicinal Chemistry)
6. State University of Pennsylvania
- Development of an automated noninvasive system for sleep restriction in rodents (with Prof. J. Fang)
7. Vanderbilt University
- The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease (with Prof C. Lindsley and Prof. D. Weaver, ACS Chemical Neuroscience, 2011).
- The Discovery and Characterization of ML297 (VU0456810), the first potent and selective activator of the GIRK potassium channel, displays anti-epileptic properties in mice (with Prof D. Weaver and Prof C. Lindsley, ACS Chemical Neuroscience, 2013).
8. SRI International.
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia (with Dr. T. Kilduff, J Clinical Investigation, 2008).
- Rodent Motor and Neuropsychological Behavior Measured in Home Cages Using the Integrated Modular Platform – SmartCageTM (with Dr. T. Khroyan)
9. Knock-in Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization. (with Dr. L. Toll, J Neurosci., 2015)