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Collaborations

1. Stanford University School of Medicine

  • Development of automated neurobehavioral assay for rodent stroke model assessments (with Prof. R. Giffard, two publications, Stroke 2011, 2013)
  • Treatment of neuropathic pain with dissolvable microneedles containing peptide GPCR antagonists (with Prof. D. Yeomans)
  • Molecular changes in the aging systemic milieu using parabiosis mice (studies led by Prof. A. Wyss-Coray, two publications, Nature, 2011; Nat. Med., 2014)
  • Gut-derived factors promote neurogenesis of CNS-neural stem cells and nudge their differentiation to an enteric-like neuronal phenotype (studies let by J Pasricha P, Gastrointestinal and Liver Physiology, 2011, Molecular Pain, 2012)
  • Reduced locomotor activity correlates with increased severity of arthritis in a mouse model of antibody-induced arthritis (with Prof. E. Mellins, Open J Rheumatol Autoimmune Dis., 2014)

2. Harvard Medical School

  • Developing a visual assessment system for retinal function/drug discovery (with Prof. D. Chen and Prof. G. Luo, Schepens Eye Research Institute Massachusetts Eye and Ear)
  • Study the interaction between nociceptin/orphanin FQ and hypocretin/orexin systems in modulation of stress-induced analgesia in rats, and tracer-suicide enzyme-prodrug for selective lesions of particular neural pathways. (with Prof. D. Gerashchenko, Neuropharmacology 2011, Harvard Medical School/VA Medical Center)

3. University of California Los Angeles, David Geffen School of Medicine

  • Nicotine delivery to rodents with lung alveolar region-targeted aerosol technology (With Dr. M. Shao, Nicotine Tob Res, 2013)

4. University of California, Davis

  • Development of novel tricyclic pyrone drugs for treatment of Alzheimer’s disease (With Prof. L. Jin)

5. Kansas State University

  • Development of novel tricyclic pyrone drugs for treatment of Alzheimer’s disease and
  • Development of novel Tetracyclic Terpenes for for treatment of hypertension (With . Prof. H. Hua, Bioorganic & Medicinal Chemistry)

6. State University of Pennsylvania

  • Development of an automated noninvasive system for sleep restriction in rodents (with Prof. J. Fang)

7. Vanderbilt University

  • The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease (with Prof C. Lindsley and Prof. D. Weaver, ACS Chemical Neuroscience, 2011).
  • The Discovery and Characterization of ML297 (VU0456810), the first potent and selective activator of the GIRK potassium channel, displays anti-epileptic properties in mice (with Prof D. Weaver and Prof C. Lindsley, ACS Chemical Neuroscience, 2013).

8. SRI International.

Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia (with Dr. T. Kilduff, J Clinical Investigation, 2008).

  • Rodent Motor and Neuropsychological Behavior Measured in Home Cages Using the Integrated Modular Platform – SmartCageTM (with Dr. T. Khroyan)

9. Knock-in Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization. (with Dr. L. Toll, J Neurosci., 2015)