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Cognitive tests

Model Assay Measurements
1. Wild type mice 1.  Water Maze Assays 1 and 2. Training and probe finding time
2. Transgenic mice 2.  Barnes Maze Assays 3, and 4. Correct rate
3. Control 3.  Y-maze Assays 5 and 6. Recognition index
4. Treatment 4.  T-maze discrete-trial delayed alternation task Assays 7. Latency to entry
  5.  Novel object recognition and Novel location Recognition Assays 8. Freezing number; changes in travel distance and rearing
  6.  Social memory  
  7.  Step-through passive avoidance  
  8.  Tone- and contextual-conditioning fear